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研究業績

研究業績

2015年以降の業績集です。2014年以前の業績につきましては左記の「2014年以前の業績」を参照ください。

英文 学術論文 2015~

2015年

Yokoyama K, Yamada T, Mitani H, Yamada S, Pu S, Yamanashi T, Matsumura H, Nakagome K, Kaneko K. Relationship between hypothalamic-pituitary-adrenal axis dysregulation and insulin resistance in elderly patients with depression. Psychiatry Res. 2015; 226: 494-498.


Pu S, Nakagome K, Yamada T, Yokoyama K, Matsumura H, Nagata I, Kaneko K. Prefrontal activation predicts social functioning improvement after initial treatment in late-onset depression. J Psychiatr Res. 2015 Mar;62:62-70.

Tomioka H, Yamagata B, Kawasaki S, Pu S, Iwanami A, Hirano J, Nakagome K, Mimura M. A longitudinal functional neuroimaging study in medication-naïve depression after antidepressant treatment. PLoS One. 2015 Mar 18;10(3):e0120828.

Pu S, Nakagome K, Yamada T, Yokoyama K, Matsumura H, Yamada S, Sugie T, Miura A, Mitani H, Iwata M, Nagata I, Kaneko K. Suicidal ideation is associated with reduced prefrontal activation during a verbal fluency task in patients with major depressive disorder. J Affect Disord. 2015 Aug 1;181:9-17.

Pu S, Nakagome K, Yamada T, Matsumura H, Yokoyama K, Kaneko K, Kurosawa Y. Association between Fish Consumption and Prefrontal Function during a Cognitive Task in Male Japanese Workers: A Multi-Channel Near-Infrared Spectroscopy Study. PLoS One. 2015 Apr 28;10(4):e0123972.

Pu S, Nakagome K, Itakura M, Yamanashi T, Sugie T, Miura A, Satake T, Iwata M, Nagata I, Kaneko K. Self-reported social functioning and prefrontal hemodynamic responses during a cognitive task in schizophrenia. Psychiatry Res. 2015 Oct 30;234(1):121-9.

Hagiya K, Sumiyoshi T, Kanie A, Pu S, Kaneko K, Mogami T, Oshima S, Niwa S, Inagaki A, Ikebuchi E, Kikuchi A, Yamasaki S, Iwata K, Nakagome K. Facial expression perception correlates with verbal working memory function in schizophrenia. Psychiatry Clin Neurosci. 2015 Dec;69(12):773-81.



2016年

Pu S, Nakagome K, Miura A, Iwata M, Nagata I, Kaneko K. Associations between depressive symptoms and fronto-temporal activities during a verbal fluency task in patients with schizophrenia. Sci Rep. 2016 Jul 28;6:30685.

Pu S, Nakagome K, Yamada T, Itakura M, Yamanashi T, Yamada S, Masai M, Miura A, Yamauchi T, Satake T, Iwata M, Nagata I, Roberts DL, Kaneko K. Social cognition and prefrontal hemodynamic responses during a working memory task in schizophrenia. Sci Rep. 2016 Mar 1;6:22500.

Pu S, Nakagome K, Itakura M, Iwata M, Nagata I, Kaneko K. The association between cognitive deficits and prefrontal hemodynamic responses during performance of working memory task in patients with schizophrenia. Schizophr Res. 2016 Apr;172(1-3):114-22.

Masai M, Pu S, Yokoyama K, Matsumura H, Yamanashi T, Itakura M, Sugie T, Miura A, Nagata I, Iwata M, Kaneko K. Residual Symptoms Were Differentially Associated with Brain Function in Remitted Patients with Major Depressive Disorders. Yonago Acta Med. 2016 Mar;59(1):15-23.

Iwata M, Ishida H, Kaneko K, Shirayama Y. Learned helplessness activates hippocampal microglia in rats: A potential target for the antidepressant imipramine. Pharmacol Biochem Behav. Epub ahead (2016)

Wohleb ES, Franklin T, Iwata M, Duman RS.: Integrating neuroimmune systems in the neurobiology of depression. Nat Rev Neuroscience. 17: 497-511. (2016)

Iwata M, Ota KT, Li XY, Sakaue F, Li N, Dutheil S, Banas, M, Duric V, Yamanashi T, Kaneko K, Rasmussen K, Glasebrook A, Koester A, Song D, Jones KA., Zorn S, Smagin G, Duman RS.: Psychological stress activates the inflammasome via release of ATP and stimulation of the P2X7 receptor. Biol Psyhiatry. 80: 12-22. (2016)


2017年

Yamanashi T, Iwata M, Kamiya N, Tsunetomi K, Kajitani N, Wada N, Iitsuka T, Yamauchi T, Miura A, Pu S, Shirayama Y, Watanabe K, Duman RS, Kaneko K.Beta-hydroxybutyrate, an endogenic NLRP3 inflammasome inhibitor, attenuates stress-induced behavioral and inflammatory responses.Sci Rep. Aug 9;7(1):7677. (2017)

Itakura M, Pu S, Ohdachi H, Matsumura H, Yokoyama K, Nagata I, Kaneko K (2017). Association between social functioning and prefrontal cortex function during a verbal fluency task in schizophrenia: A near-infrared spectroscopic study. Psychiatry and Clinical Neurosciences, 71(11), 769–779.

Pu S, Setoyama S, Noda T. Association between cognitive deficits and suicidal ideation in patients with major depressive disorder. Sci Rep. 2017 Sep 14;7(1):11637.

Pu S, Nakagome K, Itakura M, Iwata M, Nagata I, Kaneko K. Association of fronto-temporal function with cognitive ability in schizophrenia. Sci Rep. 2017 Feb 16;7:42858.

Yamagata B, Takei Y, Itahashi T, Pu S, Hirano J, Mimura M, Iwanami A. Aberrant Spatial and Temporal Prefrontal Activation Patterns in Medication-Naïve Adults with ADHD. Front Psychiatry. 2017 Dec 5;8:274.

Hirano J, Takamiya A, Yamagata B, Hotta S, Miyasaka Y, Pu S, Iwanami A, Uchida H, Mimura M. Frontal and temporal cortical functional recovery after electroconvulsive therapy for depression: A longitudinal functional near-infrared spectroscopy study. J Psychiatr Res. 2017 Feb 22;91:26-35.

Terachi S, Yamada T, Pu S, Yokoyama K, Matsumura H, Kaneko K. Comparison of neurocognitive function in major depressive disorder, bipolar disorder, and schizophrenia in later life: A cross-sectional study of euthymic or remitted, non-demented patients using the Japanese version of the Brief Assessment of Cognition in Schizophrenia (BACS-J). Psychiatry Res. 2017 Apr 28;254:205-210.


2018年

Pu S, Noda T, Setoyama S, Nakagome K. Empirical evidence for discrete neurocognitive subgroups in patients with non-psychotic major depressive disorder: clinical implications. Psychol Med. 2018 Apr 22:1-13.

Pu S, Nakagome K, Itakura M, Ohtachi H, Iwata M, Nagata I, Kaneko K. Right Frontotemporal Cortex Mediates the Relationship between Cognitive Insight and Subjective Quality of Life in Patients with Schizophrenia. Front Psychiatry. 2018 Feb 2;9:16.

2019年

Pu S, Nakagome K, Satake T, Ohtachi H, Itakura M, Yamanashi T, Miura A, Yokoyama K, Matsumura H, Iwata M, Nagata I, Kaneko K. Comparison of prefrontal hemodynamic responses and cognitive deficits between adult patients with autism spectrum disorder and schizophrenia. Schizophr Res. 2019 Apr;206:420-427.

Takaesu Y, Watanabe K, Numata S, Iwata M, Kudo N, Oishi S, Takizawa T, Nemoto K, Yasuda Y, Tagata H, Tsuboi T, Tsujino N, Hashimoto N, Matsui Y, Hori H, Yamamori H, Sugiyama N, Suwa T, Kishimoto T, Hishimoto A, Usami M, Furihata R, Iwamoto K, Fujishiro H, Nakamura T, Mizuno K, Inagaki T, Katsumoto E, Tomita H, Ohi K, Muraoka H, Atake K, Iida H, Nagasawa T, Fujita J, Yamamura S, Onitsuka T, Murata A, Takayanagi Y, Noda H, Matsumura Y, Takezawa K, Iga JI, Ichihashi K, Ogasawara K, Yamada H, Inada K, Hashimoto R. Improvement of psychiatrists' clinical knowledge of the treatment guidelines for schizophrenia and major depressive disorders using the 'Effectiveness of Guidelines for Dissemination and Education in Psychiatric Treatment (EGUIDE)' project: A nationwide dissemination, education, and evaluation study. Psychiatry Clin Neurosci. 73: 642-648. (2019)

2020年

Kajitani N, Iwata M, Miura A, Tsunetomi K, Yamanashi T, Matsuo R, Nishiguchi T, Fukuda S, Nagata M, Shibushita M, Yamauchi T, Pu S, Shirayama Y, Watanabe K, Kaneko K. Prefrontal cortex infusion of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant-like effects in a rodent model of depression. Neuropsychopharmacol Rep. (2020).

Muneoka K, Oda Y, Iwata M, Iyo M, Hashimoto K, Shirayama Y., Monoaminergic Balances Predict Non-Depression-Like Phenotype in Learned Helplessness Paradigm. Neuroscience. 25: 30192-5. (2020)

Shirayama Y, Fujita Y, Oda Y, Iwata M, Muneoka K, Hashimoto K., Allopregnanolone induces antidepressant-like effects through BDNF-TrkB signaling independent from AMPA receptor activation in a rat learned helplessness model of depression., Behavioural Brain Research. Epub ahead (2020)


和文 学術論文 2015~

2015年

松村博史

生物学志向の精神医学教室での「私の精神療法」
精神療法,増刊第2号:210-214,2015


2016年

木下智裕, 長田泉美, 大立博昭, 山梨豪彦, 杉江拓也, 横山勝利, 山内崇平, 兼子幸一.
100歳を超えて初発しparoxetineが奏効したうつ病の1症例.
臨床精神薬理 19, 207–211, 2016


朴 盛弘兼子幸一
NIRS(Near-Infrared Spectroscopy: 光トポグラフィー検査)
精神科治療学,第31巻増刊号:30-35,2016

井上郁, 横山勝利, 正井三枝子, 兼子幸一.
辺縁系脳炎の精神症状、せん妄にblonanserinが奏功した症例.
最新精神医学 21, 160–163, 2016

岩田正明.
うつ病の炎症仮説.
Depression Frontier 2. (2016)


岩田正明.
うつ病のインフラマソーム仮説.
日本生物学的精神医学会誌. 27: 96 (2016)


2017年

板倉征史, 兼子幸一.
残遺症状, 統合失調症スペクトラム障害および他の精神病性障害群

日本臨牀 別冊 神医学症候群(第2版) 1 37, 308–312, 2017


2018年

岩田正明.
ケトン体の抗うつ作用について教えてください.
Depression Journal. (2018)

岩田正明:βヒドロキシ酪酸の抗うつ作用の発見. BIO INDUSTRY. (2018)

岩田正明:わたしの研究-研究留学のススメ-. 日本生物学的精神医学会誌. 29. 133-134. (2018)

岩田正明:ストレスと炎症. 分子精神医学. 18: 54-55, (2018)

岩田正明:うつ病の炎症性神経障害仮説. 日本生物学的精神医学会誌. 29: 193-167, (2018)


2019年

板倉征史, 兼子幸一.
気分障害の認知機能障害に対する認知リハビリテーション

臨床精神薬理 vol.22   51–57, 2019


板倉征史, 兼子幸一.
気分障害の認知機能障害に対する認知リハビリテーション

精神科治療学 34(5)   483–487, 2019

岩田正明:精神疾患に対する抗炎症療法の可能性. 日本医事新報. 4942: 40-47, (2019)


板倉征史, 兼子幸一.
統合失調症と関連疾患 妄想性障害

    月刊 精神科 vol.35   31–35, 2019


岩田正明:炎症仮説に基づく新たなうつ病治療の可能性. 精神科. 34: 435-443, (2019)


岩田正明:ケタミン:これからはじまる新しいうつ病治療. 総合病院精神医学, 31: 216-222, (2019)



2020年

板倉征史, 兼子幸一.
特集I 認知リハビリテーションの可能性: 気分障害への応用
月刊 精神科 vol.36(3)   230–234, 2020

岩田正明:うつ病の炎症性神経障害仮説. 精神科臨床Legato, 6: 22-27, (2020)