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研究業績

研究業績

2011年以降の業績集です。2010年以前の業績につきましては左記の「2010年以前の業績」を参照ください。

英文 学術論文 2011~

2011年

Pu S, Yamada T, Yokoyama K, Matsumura H, Kobayashi H, Sasaki N, Mitani H, Adachi A, Kaneko K, Nakagome K.
A multi-channel near-infrared spectroscopy study of prefrontal cortex activation during working memory task in major depressive disorder. Neurosci Res. 2011; 70: 91-7.

Iwata M, Shirayama Y, Ishida H, Hazama GI, Nakagome K.
Hippocampal astrocytes are necessary for antidepressant treatment of learned helplessness rats.
Hippocampus. 2011; 21: 877-84.

Kimoto S, Okuda A, Toritsuka M, Yamauchi T, Makinodan M, Okuda H, Tatsumi K, Nakamura Y, Wanaka A, Kishimoto T. Olanzapine stimulates proliferation but inhibits differentiation in rat oligodendrocyte precursor cell cultures. Prog Neuropsychopharmacol Biol Psychiatry. 2011 ; 35: 1950-6.


2012年

Pu S, Yamada T, Yokoyama K, Matsumura H, Mitani H, Adachi A, Kaneko K, Nakagome K.
Reduced prefrontal cortex activation during the working memory task associated with poor social functioning in late-onset depression: multi-channel near-infrared spectroscopy study.
Psychiatry Res. 2012; 203: 222-8.

Pu S, Nakagome K, Yamada T, Yokoyama K, Matsumura H, Mitani H, Adachi A, Nagata I, Kaneko K.
The relationship between the prefrontal activation during a verbal fluency task and stress-coping style in major depressive disorder: a near-infrared spectroscopy study. J Psychiatr Res. 2012; 46: 1427-34.

Yamada T, Pu S, Yokoyama K, Matsumura H, Mitani H, Kaneko K, Nakagome K.
Fish consumption is positively associated with social functioning: a cross-sectional study in male Japanese workers. Psychiatry Res. 2012; 200: 1038-40.

Ikezawa S, Mogami T, Hayami Y, Sato I, Kato T, Kimura I, Pu S, Kaneko K, Nakagome K.
The pilot study of a Neuropsychological Educational Approach to Cognitive Remediation for patients with schizophrenia in Japan. Psychiatry Res. 2012; 195: 107-10.

Iwata M, Hazama GI, Nakagome K.
Depressive state due to isolated adrenocorticotropic hormone deficiency underlies school refusal.
Psychiatry Clin Neurosci. 2012; 66: 243-4

Ishida H, Iwata M, Shirayama Y, Muneoka K
Neural Activation by Milnacipran and Memory Extinction
Journal of Behavioral and Brain Science. 2012 2; 141-145


2013年

Iwata M, Ota KT, Duman RS.
The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses.
Brain Behav Immun. 2013; 31: 105-14.

Yamagata Y, Kaneko K, Kase D, Ishihara H, Nairn AC, Obata K, Imoto K.
Regulation of ERK1/2 mitogen-activated protein kinase by NMDA-receptor-induced seizure activity in cortical slices.
Brain Res. 2013 24;1507:1-10.

Kaneda Y, Ohmori T, Okahisa Y, Sumiyoshi T, Pu S, Ueoka Y, Takaki M, Nakagome K, Sora I. Measurement and Treatment Research to ImproveCognition in Schizophrenia Consensus Cognitive Battery: Validation of the Japanese version. Psychiatry Clin Neurosci., 67, 182-8, 2013.

Sora I, Kaneda Y, Sato T, Sumiyoshi C, Ohmori T, Okahisa Y, Sumiyoshi T, Pu S, Miura T, Ueoka Y, Takaki M, Miyazawa S, Nishiyama S, Nakagome K, Knaba S. The MATRICS Consensus Cognitive Battery (MCCB):development of a Japanese version. Psychiatry Clin Neurosci. 2013.

Pu S, Nakagome K, Yamada T, Yokoyama K, Matsumura H, Terachi S, Mitani H, Adachi A, Kaneko K. Relationship between prefrontal function during a cognitive task and social functioning in male Japanese workers: A multi-channel near-infrared spectroscopy study. Psychiatry Res. 2013.

Pu S, Nakagome K, Yamada T, Itakura M, Satake T, Ishida H, Nagata I, Kaneko K. Association between cognitive insight and prefrontal function during a cognitive task in schizophrenia: A multichannel near-infrared spectroscopy study. Schizophrenia Res. 2013.

Pu S, Nakagome K, Yamada T, Yokoyama K, Itakura M, Satake T, Ishida H, Nagata I, Kaneko K. Association between subjective well-being and prefrontal function during a cognitive task in schizophrenia: Amulti-channel near-infrared spectroscopy study. Schizophrenia Res. 2013.

Chuang C, Nakagome K, Pu S, Lan T, Lee C, Sun C. Discriminant analysis of functional optical topography for schizophrenia diagnosis. Journal of Bilmedical Optics. 2013 .

Takizawa R, Fukuda M, Kawasaki S, Kasai K, Mimura M, Pu S, Noda T, Niwa SI, Okazaki Y; on behalf of the Joint Project for Psychiatric Application of Near-Infrared Spectroscopy (JPSY-NIRS) Group. Neuroimaging-aided differential diagnosis of the depressive state. Neuroimage. 2013.

Ota KT, Liu RJ, Voleti B, Maldonado-Aviles JG, Duric V, Iwata M, Dutheil S, Duman C, Boikess S, Lewis DA, Stockmeier CA, DiLeone RJ, Rex C, Aghajanian GK, Duman RS. (2014) REDD1 is essential for stress-induced synaptic loss and depressive behavior. Nat Med, 20: 531-535.


2014年

Yokoyama K, Yamada T, Terachi S, Pu S, Ohta Y, Yamanashi T, Matsumura H, Nakagome K, Kaneko K.
Milnacipran influences the indexes of I-metaiodobenzylguanidine scintigraphy in elderly depressed patients.
Psychiatry Clin Neurosci. 2014 ; 68: 169-75.

Pu S, Nakagome K, Yamada T, Itakura M, Satake T, Ishida H, Nagata I, Kaneko K. Association between prefrontal hemodynamic responses during a cognitive task and subjective quality of life in schizophrenia. Schizophr Res. 2014 ; 152: 319-21.

Pu S, Nakagome K, Yamada T, Ikezawa S, Itakura M, Satake T, Ishida H, Nagata I, Mogami T, Kaneko K. A pilot study on the effects of cognitive remediation on hemodynamic responses in the prefrontal cortices of patients with schizophrenia: a multi-channel near-infrared spectroscopy study. Schizophr Res. 2014; 153: 87-95.

Kanie A, Hagiya K, Ashida S, Pu S, Kaneko K, Mogami T, Oshima S, Motoya M, Niwa SI, Inagaki A, Ikebuchi E, Kikuchi A, Yamasaki S, Iwata K, Roberts DL, Nakagome K. New instrument for measuring multiple domains of social cognition: Construct validity of the Social Cognition Screening Questionnaire (Japanese version). Psychiatry Clin Neurosci. 2014 Mar 11. doi: 10.1111/pcn.12181.

Pu S, Nakagome K, Yamada T, Yokoyama K, Matsumura H, Mitani H, Adachi A, Kaneko K. Association between social functioning and prefrontal hemodynamic responses in elderly adults. Behav Brain Res. 2014 Oct 1;272:32-9.


2015年

Yokoyama K, Yamada T, Mitani H, Yamada S, Pu S, Yamanashi T, Matsumura H, Nakagome K, Kaneko K. Relationship between hypothalamic-pituitary-adrenal axis dysregulation and insulin resistance in elderly patients with depression. Psychiatry Res. 2015; 226: 494-498.


Pu S, Nakagome K, Yamada T, Yokoyama K, Matsumura H, Nagata I, Kaneko K. Prefrontal activation predicts social functioning improvement after initial treatment in late-onset depression. J Psychiatr Res. 2015 Mar;62:62-70.

Tomioka H, Yamagata B, Kawasaki S, Pu S, Iwanami A, Hirano J, Nakagome K, Mimura M. A longitudinal functional neuroimaging study in medication-naïve depression after antidepressant treatment. PLoS One. 2015 Mar 18;10(3):e0120828.

Pu S, Nakagome K, Yamada T, Yokoyama K, Matsumura H, Yamada S, Sugie T, Miura A, Mitani H, Iwata M, Nagata I, Kaneko K. Suicidal ideation is associated with reduced prefrontal activation during a verbal fluency task in patients with major depressive disorder. J Affect Disord. 2015 Aug 1;181:9-17.

Pu S, Nakagome K, Yamada T, Matsumura H, Yokoyama K, Kaneko K, Kurosawa Y. Association between Fish Consumption and Prefrontal Function during a Cognitive Task in Male Japanese Workers: A Multi-Channel Near-Infrared Spectroscopy Study. PLoS One. 2015 Apr 28;10(4):e0123972.

Pu S, Nakagome K, Itakura M, Yamanashi T, Sugie T, Miura A, Satake T, Iwata M, Nagata I, Kaneko K. Self-reported social functioning and prefrontal hemodynamic responses during a cognitive task in schizophrenia. Psychiatry Res. 2015 Oct 30;234(1):121-9.

Hagiya K, Sumiyoshi T, Kanie A, Pu S, Kaneko K, Mogami T, Oshima S, Niwa S, Inagaki A, Ikebuchi E, Kikuchi A, Yamasaki S, Iwata K, Nakagome K. Facial expression perception correlates with verbal working memory function in schizophrenia. Psychiatry Clin Neurosci. 2015 Dec;69(12):773-81.



2016年

Pu S, Nakagome K, Miura A, Iwata M, Nagata I, Kaneko K. Associations between depressive symptoms and fronto-temporal activities during a verbal fluency task in patients with schizophrenia. Sci Rep. 2016 Jul 28;6:30685.

Pu S, Nakagome K, Yamada T, Itakura M, Yamanashi T, Yamada S, Masai M, Miura A, Yamauchi T, Satake T, Iwata M, Nagata I, Roberts DL, Kaneko K. Social cognition and prefrontal hemodynamic responses during a working memory task in schizophrenia. Sci Rep. 2016 Mar 1;6:22500.

Pu S, Nakagome K, Itakura M, Iwata M, Nagata I, Kaneko K. The association between cognitive deficits and prefrontal hemodynamic responses during performance of working memory task in patients with schizophrenia. Schizophr Res. 2016 Apr;172(1-3):114-22.

Masai M, Pu S, Yokoyama K, Matsumura H, Yamanashi T, Itakura M, Sugie T, Miura A, Nagata I, Iwata M, Kaneko K. Residual Symptoms Were Differentially Associated with Brain Function in Remitted Patients with Major Depressive Disorders. Yonago Acta Med. 2016 Mar;59(1):15-23.

Iwata M, Ishida H, Kaneko K, Shirayama Y. Learned helplessness activates hippocampal microglia in rats: A potential target for the antidepressant imipramine. Pharmacol Biochem Behav. Epub ahead (2016)

Wohleb ES, Franklin T, Iwata M, Duman RS.: Integrating neuroimmune systems in the neurobiology of depression. Nat Rev Neuroscience. 17: 497-511. (2016)

Iwata M, Ota KT, Li XY, Sakaue F, Li N, Dutheil S, Banas, M, Duric V, Yamanashi T, Kaneko K, Rasmussen K, Glasebrook A, Koester A, Song D, Jones KA., Zorn S, Smagin G, Duman RS.: Psychological stress activates the inflammasome via release of ATP and stimulation of the P2X7 receptor. Biol Psyhiatry. 80: 12-22. (2016)

和文 学術論文 2011~

2011年

中込和幸兼子幸一,最上多美子
社会認知ならびに対人関係のトレーニング(SCIT)治療マニュアル


最上多美子,池澤 聰兼子幸一朴 盛弘中込和幸. 
統合失調症の認知機能障害に対する認知矯正療法の効果. 
日本神経精神薬理学雑誌 2011; 31(5-6):245-249.


2012年

兼子幸一山田武史佐竹隆宏松村博史横山勝利朴盛弘
精神医学・心理学・精神看護学辞典

長田泉美
神経心理学的側面からみたlithiumの効果
臨床精神薬理

長田泉美
統合失調症維持期と再発予防に向けた治療ストラテジー
統合失調症治療の新たなストラテジー

松村博史小林北斗佐竹隆宏兼子幸一.
解離状態における粗暴行為を呈した,発達障害の高校生男児の1症例.
精神科,21(6):737-741,2012


2013年

長田泉美
てんかん
今日の治療指針

岩田正明
マイクログリアと気分障害
脳21

岩田正明
ストレスがIL-1βを放出させる機序の解明:うつ病治療の新たなターゲットを探して
Depression Frontier 11 : 79-86, 2013


2014年

朴盛弘石田寿人兼子幸一
Depressionの光トポグラフィー.
神経内科,2013; 79(1): 42-49.

富岡 大,川崎真護,岩波 明,野田隆政,兼子幸一朴 盛弘,三村 将,中込和幸
MEDIX, 2013; 58: 4-9.

松村博史兼子幸一.
激しい行動化により半年間にわたり頻回の入院を要し,広汎性発達障害が疑われた思春期女児の1例.
精神科,25(1):108-112,2014

横山勝利兼子幸一
認知機能に対する副作用.
臨床精神医学,43(11): 1549-1552, 2014.

朴盛弘岩田正明兼子幸一
特集I:光トポグラフィー検査をどう使いこなすか―うつ病のどのような臨床徴候を反映するのか.
精神科,25(3): 283-289,2014.

岩田正明
ミクログリアとストレス
分子精神医学 , 14: 15-22, 2014

松村博史
うつ病概念の混乱
心と社会,45(4):14-20,2014


2015年

松村博史
生物学志向の精神医学教室での「私の精神療法」
精神療法,増刊第2号:210-214,2015


2016年

木下智裕, 長田泉美, 大立博昭, 山梨豪彦, 杉江拓也, 横山勝利, 山内崇平, 兼子幸一.
100歳を超えて初発しparoxetineが奏効したうつ病の1症例.
臨床精神薬理 19, 207–211, 2016


朴 盛弘兼子幸一
NIRS(Near-Infrared Spectroscopy: 光トポグラフィー検査)
精神科治療学,第31巻増刊号:30-35,2016

井上郁, 横山勝利, 正井三枝子, 兼子幸一.
辺縁系脳炎の精神症状、せん妄にblonanserinが奏功した症例.
最新精神医学 21, 160–163, 2016

岩田正明.
うつ病の炎症仮説.
Depression Frontier 2. (2016)